V70L (p.Val70Leu) variant of SOS1 (Son of sevenless homolog 1)
V70L (p.Val70Leu) in SOS1 (Son of sevenless homolog 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
V70L (p.Val70Leu) variant details
- p.Val70Leu
- gnomAD rs1671635364
- Missense
- Variant Prioritization Score for Impact Estimate 0.706
- REVEL 0.67
- CADD 24.60
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available