V24E (p.Val24Glu) variant of SOS1 (Son of sevenless homolog 1)
V24E (p.Val24Glu) in SOS1 (Son of sevenless homolog 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
V24E (p.Val24Glu) variant details
- p.Val24Glu
- cosmic curated COSV67673
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- REVEL 0.63
- CADD 24.20
- PolyPhen-2 0.11
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available