S104F (p.Ser104Phe) variant of SOS1 (Son of sevenless homolog 1)
S104F (p.Ser104Phe) in SOS1 (Son of sevenless homolog 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
S104F (p.Ser104Phe) variant details
- p.Ser104Phe
- ExAC rs752017140
- TOPMed rs752017140
- gnomAD rs752017140
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.13
- CADD 21.00
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available