R65* (p.Arg65Ter) variant of SOS1 (Son of sevenless homolog 1)
R65* (p.Arg65Ter) in SOS1 (Son of sevenless homolog 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
R65* (p.Arg65Ter) variant details
- p.Arg65Ter
- gnomAD rs1303674298
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.855
- CADD 37.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available