N15K (p.Asn15Lys) variant of SOS1 (Son of sevenless homolog 1)
N15K (p.Asn15Lys) in SOS1 (Son of sevenless homolog 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
N15K (p.Asn15Lys) variant details
- p.Asn15Lys
- ExAC rs765652390
- TOPMed rs765652390
- gnomAD rs765652390
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.41
- CADD 23.50
- PolyPhen-2 0.04
- SIFT 0.00
- Population evidence available
- Structural context available