D69A (p.Asp69Ala) variant of SOS1 (Son of sevenless homolog 1)
D69A (p.Asp69Ala) in SOS1 (Son of sevenless homolog 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
D69A (p.Asp69Ala) variant details
- p.Asp69Ala
- Ensembl rs1558497933
- Missense
- Variant Prioritization Score for Impact Estimate 0.749
- REVEL 0.82
- CADD 27.30
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available