A67V (p.Ala67Val) variant of SOS1 (Son of sevenless homolog 1)
A67V (p.Ala67Val) in SOS1 (Son of sevenless homolog 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A67V (p.Ala67Val) variant details
- p.Ala67Val
- gnomAD rs1445719629
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.21
- CADD 16.30
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available