I125T (p.Ile125Thr) variant of SLC2A2 (P11168)
I125T (p.Ile125Thr) in SLC2A2 (P11168) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
I125T (p.Ile125Thr) variant details
- p.Ile125Thr
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.20
- CADD 22.00
- PolyPhen-2 0.01
- SIFT 0.35
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available