W99S (p.Trp99Ser) variant of SLC22A8 (Organic anion transporter 3)
W99S (p.Trp99Ser) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
W99S (p.Trp99Ser) variant details
- p.Trp99Ser
- TOPMed rs928963210
- gnomAD rs928963210
- Missense
- Variant Prioritization Score for Impact Estimate 0.814
- REVEL 0.82
- MetaLR 0.80
- MetaSVM 0.78
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available