W60C (p.Trp60Cys) variant of SLC22A8 (Organic anion transporter 3)
W60C (p.Trp60Cys) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
W60C (p.Trp60Cys) variant details
- p.Trp60Cys
- cosmic curated COSV60326
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.13
- MetaLR 0.10
- MetaSVM -1.06
- CADD 22.70
- PolyPhen-2 0.34
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available