W112R (p.Trp112Arg) variant of SLC22A8 (Organic anion transporter 3)
W112R (p.Trp112Arg) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
W112R (p.Trp112Arg) variant details
- p.Trp112Arg
- ExAC rs745877843
- gnomAD rs745877843
- Missense
- Variant Prioritization Score for Impact Estimate 0.74
- REVEL 0.85
- MetaLR 0.74
- MetaSVM 0.64
- CADD 28.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available