V61L (p.Val61Leu) variant of SLC22A8 (Organic anion transporter 3)
V61L (p.Val61Leu) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
V61L (p.Val61Leu) variant details
- p.Val61Leu
- cosmic curated COSV60326
- gnomAD rs1247568601
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.05
- MetaLR 0.02
- MetaSVM -0.99
- CADD 3.67
- PolyPhen-2 0.01
- SIFT 0.52
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available