V46I (p.Val46Ile) variant of SLC22A8 (Organic anion transporter 3)
V46I (p.Val46Ile) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
V46I (p.Val46Ile) variant details
- p.Val46Ile
- gnomAD rs1385643542
- Missense
- Variant Prioritization Score for Impact Estimate 0.0602
- REVEL 0.01
- MetaLR 0.07
- MetaSVM -1.03
- CADD 0.06
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available