V10M (p.Val10Met) variant of SLC22A8 (Organic anion transporter 3)
V10M (p.Val10Met) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
V10M (p.Val10Met) variant details
- p.Val10Met
- ExAC rs770889008
- TOPMed rs770889008
- gnomAD rs770889008
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.37
- MetaLR 0.41
- MetaSVM -0.27
- CADD 18.20
- PolyPhen-2 0.95
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available