V10L (p.Val10Leu) variant of SLC22A8 (Organic anion transporter 3)
V10L (p.Val10Leu) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V10L (p.Val10Leu) variant details
- p.Val10Leu
- ExAC rs770889008
- TOPMed rs770889008
- gnomAD rs770889008
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.13
- MetaLR 0.15
- MetaSVM -0.90
- CADD 4.86
- PolyPhen-2 0.10
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available