T104I (p.Thr104Ile) variant of SLC22A8 (Organic anion transporter 3)
T104I (p.Thr104Ile) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
T104I (p.Thr104Ile) variant details
- p.Thr104Ile
- TOPMed rs2086654021
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.06
- MetaLR 0.14
- MetaSVM -0.90
- CADD 22.30
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available