S127Y (p.Ser127Tyr) variant of SLC22A8 (Organic anion transporter 3)
S127Y (p.Ser127Tyr) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
S127Y (p.Ser127Tyr) variant details
- p.Ser127Tyr
- TOPMed rs2086484365
- gnomAD rs2086484365
- Missense
- Variant Prioritization Score for Impact Estimate 0.62
- REVEL 0.60
- MetaLR 0.56
- MetaSVM 0.36
- CADD 27.30
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available