R90K (p.Arg90Lys) variant of SLC22A8 (Organic anion transporter 3)
R90K (p.Arg90Lys) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R90K (p.Arg90Lys) variant details
- p.Arg90Lys
- gnomAD rs1228653354
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.13
- MetaLR 0.15
- MetaSVM -0.98
- CADD 9.28
- PolyPhen-2 0.10
- SIFT 0.84
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available