P94S (p.Pro94Ser) variant of SLC22A8 (Organic anion transporter 3)
P94S (p.Pro94Ser) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
P94S (p.Pro94Ser) variant details
- p.Pro94Ser
- cosmic curated COSV60327
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.48
- MetaLR 0.53
- MetaSVM -0.06
- CADD 23.10
- PolyPhen-2 0.45
- SIFT 0.09
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available