P85S (p.Pro85Ser) variant of SLC22A8 (Organic anion transporter 3)
P85S (p.Pro85Ser) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P85S (p.Pro85Ser) variant details
- p.Pro85Ser
- cosmic curated COSV60326
- TOPMed rs1212292629
- gnomAD rs1212292629
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.21
- MetaLR 0.22
- MetaSVM -0.77
- CADD 16.80
- PolyPhen-2 0.15
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available