P70T (p.Pro70Thr) variant of SLC22A8 (Organic anion transporter 3)
P70T (p.Pro70Thr) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
P70T (p.Pro70Thr) variant details
- p.Pro70Thr
- ExAC rs758755852
- gnomAD rs758755852
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.21
- MetaLR 0.29
- MetaSVM -0.63
- CADD 14.80
- PolyPhen-2 0.22
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available