P70A (p.Pro70Ala) variant of SLC22A8 (Organic anion transporter 3)
P70A (p.Pro70Ala) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
P70A (p.Pro70Ala) variant details
- p.Pro70Ala
- ExAC rs758755852
- gnomAD rs758755852
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.41
- MetaLR 0.40
- MetaSVM -0.31
- CADD 14.70
- PolyPhen-2 0.78
- SIFT 0.05
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available