P51L (p.Pro51Leu) variant of SLC22A8 (Organic anion transporter 3)
P51L (p.Pro51Leu) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P51L (p.Pro51Leu) variant details
- p.Pro51Leu
- cosmic curated COSV60327
- ExAC rs761564053
- TOPMed rs761564053
- gnomAD rs761564053
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.09
- MetaLR 0.06
- MetaSVM -1.03
- CADD 3.15
- PolyPhen-2 0.01
- SIFT 0.61
- Most common in the East Asian population (allele frequency 0.00035)
- Structural context available