N35Y (p.Asn35Tyr) variant of SLC22A8 (Organic anion transporter 3)
N35Y (p.Asn35Tyr) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
N35Y (p.Asn35Tyr) variant details
- p.Asn35Tyr
- cosmic curated COSV60327
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.14
- MetaLR 0.18
- MetaSVM -0.93
- CADD 20.80
- PolyPhen-2 0.30
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available