N35K (p.Asn35Lys) variant of SLC22A8 (Organic anion transporter 3)
N35K (p.Asn35Lys) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
N35K (p.Asn35Lys) variant details
- p.Asn35Lys
- ExAC rs752939398
- gnomAD rs752939398
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.37
- MetaLR 0.29
- MetaSVM -0.62
- CADD 22.60
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00083)
- Structural context available