N117S (p.Asn117Ser) variant of SLC22A8 (Organic anion transporter 3)
N117S (p.Asn117Ser) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
N117S (p.Asn117Ser) variant details
- p.Asn117Ser
- ExAC rs777806244
- gnomAD rs777806244
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.20
- MetaLR 0.13
- MetaSVM -0.95
- CADD 0.29
- PolyPhen-2 0.00
- SIFT 0.70
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available