L96P (p.Leu96Pro) variant of SLC22A8 (Organic anion transporter 3)
L96P (p.Leu96Pro) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
L96P (p.Leu96Pro) variant details
- p.Leu96Pro
- TOPMed rs2086654346
- gnomAD rs2086654346
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.57
- MetaLR 0.46
- MetaSVM -0.37
- CADD 17.70
- SIFT 0.34
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available