L62F (p.Leu62Phe) variant of SLC22A8 (Organic anion transporter 3)
L62F (p.Leu62Phe) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L62F (p.Leu62Phe) variant details
- p.Leu62Phe
- Ensembl rs2086655854
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.11
- MetaLR 0.11
- MetaSVM -1.01
- CADD 14.20
- PolyPhen-2 0.18
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available