L37P (p.Leu37Pro) variant of SLC22A8 (Organic anion transporter 3)
L37P (p.Leu37Pro) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
L37P (p.Leu37Pro) variant details
- p.Leu37Pro
- Ensembl rs1565303911
- Missense
- Variant Prioritization Score for Impact Estimate 0.626
- REVEL 0.75
- MetaLR 0.55
- MetaSVM 0.28
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available