L36M (p.Leu36Met) variant of SLC22A8 (Organic anion transporter 3)
L36M (p.Leu36Met) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
L36M (p.Leu36Met) variant details
- p.Leu36Met
- ExAC rs765415190
- TOPMed rs765415190
- gnomAD rs765415190
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.30
- MetaLR 0.27
- MetaSVM -0.46
- CADD 20.20
- PolyPhen-2 0.77
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available