I108V (p.Ile108Val) variant of SLC22A8 (Organic anion transporter 3)
I108V (p.Ile108Val) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
I108V (p.Ile108Val) variant details
- p.Ile108Val
- TOPMed rs2086653913
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.30
- MetaLR 0.36
- MetaSVM -0.55
- CADD 24.60
- PolyPhen-2 0.95
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available