I108T (p.Ile108Thr) variant of SLC22A8 (Organic anion transporter 3)
I108T (p.Ile108Thr) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
I108T (p.Ile108Thr) variant details
- p.Ile108Thr
- TOPMed rs1373884407
- Missense
- Variant Prioritization Score for Impact Estimate 0.506
- REVEL 0.56
- MetaLR 0.43
- MetaSVM -0.43
- CADD 26.00
- PolyPhen-2 0.95
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available