H78Y (p.His78Tyr) variant of SLC22A8 (Organic anion transporter 3)
H78Y (p.His78Tyr) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
H78Y (p.His78Tyr) variant details
- p.His78Tyr
- TOPMed rs2086655124
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.09
- MetaLR 0.14
- MetaSVM -0.99
- CADD 1.41
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available