H53Y (p.His53Tyr) variant of SLC22A8 (Organic anion transporter 3)
H53Y (p.His53Tyr) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
H53Y (p.His53Tyr) variant details
- p.His53Tyr
- gnomAD rs1243707448
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.10
- MetaLR 0.04
- MetaSVM -1.00
- CADD 13.10
- PolyPhen-2 0.00
- SIFT 0.85
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available