H47R (p.His47Arg) variant of SLC22A8 (Organic anion transporter 3)
H47R (p.His47Arg) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
H47R (p.His47Arg) variant details
- p.His47Arg
- Ensembl rs2086656601
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.55
- MetaLR 0.48
- MetaSVM 0.16
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 7.2e-06)
- Structural context available