G65D (p.Gly65Asp) variant of SLC22A8 (Organic anion transporter 3)
G65D (p.Gly65Asp) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G65D (p.Gly65Asp) variant details
- p.Gly65Asp
- ExAC rs747501154
- gnomAD rs747501154
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.13
- MetaLR 0.08
- MetaSVM -0.99
- CADD 0.03
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available