G132S (p.Gly132Ser) variant of SLC22A8 (Organic anion transporter 3)
G132S (p.Gly132Ser) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
G132S (p.Gly132Ser) variant details
- p.Gly132Ser
- gnomAD rs1186012350
- Missense
- Variant Prioritization Score for Impact Estimate 0.83
- REVEL 0.88
- MetaLR 0.73
- MetaSVM 0.65
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available