F18L (p.Phe18Leu) variant of SLC22A8 (Organic anion transporter 3)
F18L (p.Phe18Leu) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
F18L (p.Phe18Leu) variant details
- p.Phe18Leu
- TOPMed rs1348256124
- gnomAD rs1348256124
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.08
- MetaLR 0.04
- MetaSVM -1.02
- CADD 0.51
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available