F129L (p.Phe129Leu) variant of SLC22A8 (Organic anion transporter 3)
F129L (p.Phe129Leu) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
F129L (p.Phe129Leu) variant details
- p.Phe129Leu
- rs11568479
- UniProt VAR 030146
- TOPMed rs11568479
- gnomAD rs11568479
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.16
- MetaLR 0.25
- MetaSVM -0.50
- CADD 29.00
- PolyPhen-2 0.51
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available