E93K (p.Glu93Lys) variant of SLC22A8 (Organic anion transporter 3)
E93K (p.Glu93Lys) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
E93K (p.Glu93Lys) variant details
- p.Glu93Lys
- cosmic curated COSV10460
- ExAC rs769406017
- gnomAD rs769406017
- Missense
- Variant Prioritization Score for Impact Estimate 0.509
- REVEL 0.37
- MetaLR 0.48
- MetaSVM -0.04
- CADD 22.80
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available