E111K (p.Glu111Lys) variant of SLC22A8 (Organic anion transporter 3)
E111K (p.Glu111Lys) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
E111K (p.Glu111Lys) variant details
- p.Glu111Lys
- gnomAD rs1201305593
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- REVEL 0.50
- MetaLR 0.41
- MetaSVM -0.32
- CADD 32.00
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available