E111D (p.Glu111Asp) variant of SLC22A8 (Organic anion transporter 3)
E111D (p.Glu111Asp) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
E111D (p.Glu111Asp) variant details
- p.Glu111Asp
- Ensembl rs2086653678
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.40
- MetaLR 0.32
- MetaSVM -0.48
- CADD 35.00
- PolyPhen-2 0.85
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available