D8H (p.Asp8His) variant of SLC22A8 (Organic anion transporter 3)
D8H (p.Asp8His) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
D8H (p.Asp8His) variant details
- p.Asp8His
- ESP rs143865155
- ExAC rs143865155
- TOPMed rs143865155
- gnomAD rs143865155
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.11
- MetaLR 0.19
- MetaSVM -0.69
- CADD 22.60
- PolyPhen-2 0.08
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available