D113N (p.Asp113Asn) variant of SLC22A8 (Organic anion transporter 3)
D113N (p.Asp113Asn) in SLC22A8 (Organic anion transporter 3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D113N (p.Asp113Asn) variant details
- p.Asp113Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.14
- MetaLR 0.12
- MetaSVM -0.94
- CADD 22.00
- PolyPhen-2 0.21
- SIFT 0.06
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available