D106N (p.Asp106Asn) variant of SLC22A8 (Organic anion transporter 3)
D106N (p.Asp106Asn) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
D106N (p.Asp106Asn) variant details
- p.Asp106Asn
- cosmic curated COSV10460
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.10
- MetaLR 0.11
- MetaSVM -1.00
- CADD 17.10
- PolyPhen-2 0.02
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available