C95Y (p.Cys95Tyr) variant of SLC22A8 (Organic anion transporter 3)
C95Y (p.Cys95Tyr) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
C95Y (p.Cys95Tyr) variant details
- p.Cys95Tyr
- TOPMed rs955842693
- Missense
- Variant Prioritization Score for Impact Estimate 0.853
- REVEL 0.90
- MetaLR 0.84
- MetaSVM 0.95
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available