A91S (p.Ala91Ser) variant of SLC22A8 (Organic anion transporter 3)
A91S (p.Ala91Ser) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A91S (p.Ala91Ser) variant details
- p.Ala91Ser
- gnomAD rs1301652904
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.04
- MetaLR 0.13
- MetaSVM -1.03
- CADD 8.88
- PolyPhen-2 0.02
- SIFT 0.55
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available