A22P (p.Ala22Pro) variant of SLC22A8 (Organic anion transporter 3)
A22P (p.Ala22Pro) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A22P (p.Ala22Pro) variant details
- p.Ala22Pro
- gnomAD rs1300541678
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.32
- MetaLR 0.18
- MetaSVM -0.90
- CADD 4.99
- PolyPhen-2 0.71
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available