A131G (p.Ala131Gly) variant of SLC22A8 (Organic anion transporter 3)
A131G (p.Ala131Gly) in SLC22A8 (Organic anion transporter 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
A131G (p.Ala131Gly) variant details
- p.Ala131Gly
- gnomAD rs1241862157
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.40
- MetaLR 0.40
- MetaSVM -0.23
- CADD 22.10
- PolyPhen-2 0.21
- SIFT 0.38
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available