T92S (p.Thr92Ser) variant of SERPINC1 (Antithrombin-III)
T92S (p.Thr92Ser) in SERPINC1 (Antithrombin-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T92S (p.Thr92Ser) variant details
- p.Thr92Ser
- gnomAD rs1253973125
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.30
- CADD 23.30
- PolyPhen-2 0.46
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available